Culture media selection for mass production of Isaria fumosorosea and Isaria farinosa

Culture Media Selection for Mass Production of Isaria fumosorosea and Isaria farinosa

This work investigated the production of the fungi Isaria fumosorosea and Isaria farinosa in biphasic fermentation using agro-industrial products and residues. Combinations of natural liquid substrates, alternative to the complete medium and potato dextrose medium, were evaluated. The best liquid media were sugarcane molasses + rice broth, rice broth + yeast and sugarcane molasses + yeast + ric...

Ionizing radiation-induced mutagenesis in Isaria fumosorosea

PTP1B Inhibitors from the Entomogenous Fungi Isaria fumosorosea.

Protein tyrosine phosphatase 1B (PTP1B) is implicated as a negative regulator of insulin receptor (IR) signaling and a potential drug target for the treatment of type II diabetes and other associated metabolic syndromes. Thus, small molecule inhibitors of PTP1B can be considered as an attractive approach for the design of new therapeutic agents of type II diabetes and cancer diseases. In a cont...

Lack of resistance development in Bemisia tabaci to Isaria fumosorosea after multiple generations of selection

The emergence of insecticide resistant insect pests is of significant concern worldwide. The whitefly, Bemisia tabaci, is an important agricultural pest and has shown incredible resilience developing resistance to a number of chemical pesticides. Entomopathogenic fungi such as Isaria fumosorosea offer an attractive alternative to chemical pesticides for insect control, and this fungus has been ...

Cycloaspeptides F and G, Cyclic Pentapeptides from a Cordyceps-colonizing isolate of Isaria farinosa.

Cycloaspeptides F (1) and G (2), two new cyclic pentapeptides, and the known cycloaspeptides A (3), C (4), and bisdethiodi(methylthio)hyalodendrin (5) have been isolated from the crude extract of the fungus Isaria farinosa that colonizes Cordyceps sinensis. The structures of 1 and 2 were elucidated primarily by NMR and MS methods. The absolute configuration of 1 was assigned using Marfey's meth...